Welcome to Sabbiotech!     
Email:info@signalwayantibody.com
Welcome Login Register My Cart(0,$0.00)
Location： Home > Mouse Monoclonal Antibodies > SLINGSHOT-1L Antibody

SLINGSHOT-1L Antibody#48407

Datasheet PDF
Availability： Yes
Total Amount:$
ADD TO CART
Detail Pictures Description Publish(0) Other
Product Detail

Product NameSLINGSHOT-1L Antibody

Clone No.G9-C11

Host SpeciesMouse

ClonalityMonoclonal

PurificationProA affinity purified

ApplicationsIHC, FC

Species ReactivityHu

Immunogen DescRecombinant protein

ConjugateUnconjugated

Other NamesAW551225 antibody
Coro1c antibody
coronin, actin binding protein 1C antibody
Gm1394 antibody
Gm1395 antibody
hSSH-1L antibody
mSSH 1L antibody
OTTMUSP00000031415 antibody
Protein phosphatase Slingshot homolog 1 antibody
Slingshot 1 antibody
slingshot 1L antibody
slingshot homolog 1 antibody
slingshot like 1 antibody
Slingshot1 antibody
SSH 1 antibody
SSH 1L antibody
SSH-1L antibody
SSH-like protein 1 antibody
Ssh1 antibody
SSH1_HUMAN antibody

Accession NoSwiss-Prot#:Q8WYL5

Uniprot Q8WYL5

Gene ID 54434;

Calculated MW116 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details

IHC: 1:50-1:200


FC: 1:50-1:100
Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissue using anti- Slingshot homolog 1 antibody. Counter stained with hematoxylin.
Flow cytometric analysis of Hela cells with Slingshot homolog 1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
Slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

If you have published an article using product 48407, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
;

QUICK NAV

New Products

Cell Signal Transduction

Cancer

Stem Cell

Neuroscience

Help and Support

Contact Us

Terms

Privacy Policy

support

Distributors