Product Detail
Product NameCD200 Antibody
Clone No.B11-E8
Host SpeciesMouse
ClonalityMonoclonal
PurificationProA affinity purified
ApplicationsWB, FC
Species ReactivityHu
Immunogen DescRecombinant protein
ConjugateUnconjugated
Other NamesAntigen identified by monoclonal antibody
MRC OX 2 antibody
CD200 antibody
CD200 antigen antibody
CD200 molecule antibody
MOX1 antibody
MOX2 antibody
MRC antibody
MRC OX 2 antigen antibody
My033 antibody
OX 2 antibody
OX 2 membrane glycoprotein precursor antibody
OX-2 membrane glycoprotein antibody
OX2G antibody
OX2G_HUMAN antibody
Accession NoSwiss-Prot#:P41217
Uniprot
P41217
Gene ID
4345;
Calculated MW31 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:2,000
Western blot analysis of CD200 on human CD200 recombinant protein using anti- CD200 antibody at 1/1,000 dilution
Western blot analysis of CD200 on HEK293 (1) and CD200-hIgGFc transfected HEK293 (2) cell lysate using anti-CD200 antibody at 1/1,000 dilution.
OX2 (CD200, MOX2), a member of the immunoglobulin superfamily (IgSF), is a 248 residue cell surface glycoprotein that is expressed in lymphoid cells, neurons, and endothelium. OX2 receptor (OX2R) is a membrane protein with up to 70% of its weight derived from N-linked glycosylation, and it is primarily expressed in lymphoid and neuronal tissue. Phylogenetic analysis of OX2R with respect to other leukocyte IgSF glycoproteins suggests that OXR2 and OX2 share a common ancestral protein. The cytoplasmic portion of OX2R contains NPXY motifs that are known to interact with PTB/PID binding domains. The interaction between OX2 and OX2R may contribute to pathways that suppress and limit macrophage induced inflammatory damage in tissue.
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