Product Detail
Product NameCDCP1 Antibody
Clone No.G3-H11
Host SpeciesMouse
ClonalityMonoclonal
PurificationProA affinity purified
ApplicationsWB, IHC
Species ReactivityHu
Immunogen DescRecombinant protein
ConjugateUnconjugated
Other Names9030022E12Rik antibody
AA409659 antibody
CD 318 antibody
CD_antigen=CD318 antibody
CD318 antibody
CD318 antigen antibody
CDCP 1 antibody
Cdcp1 antibody
CDCP1_HUMAN antibody
CUB domain containing protein 1 antibody
CUB domain-containing protein 1 antibody
E030027H19Rik antibody
FLJ13772 antibody
FLJ22375 antibody
FLJ22969 antibody
Membrane glycoprotein gp140 antibody
MGC31813 antibody
OTTHUMP00000164120 antibody
OTTHUMP00000209568 antibody
RGD1305578 antibody
SIMA 135 antibody
SIMA135 antibody
Subtractive immunization M plus HEp3 associated 135 kDa protein antibody
Subtractive immunization M plus HEp3-associated 135 kDa protein antibody
Transmembrane and associated with src kinases antibody
TRASK antibody
Accession NoSwiss-Prot#:Q9H5V8
Uniprot
Q9H5V8
Gene ID
64866;
Calculated MW93 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:2,000
IHC: 1:200-1:500
Western blot analysis of CDCP1 on human CDCP1 recombinant protein using anti-CDCP1 antibody at 1/1,000 dilution.
Western blot analysis of CDCP1 on HEK293 (1) and CDCP1-hIgGFc transfected HEK293 (2) cell lysate using anti-CDCP1 antibody at 1/1,000 dilution.
Flow cytometric analysis of Hela cells with CDCP1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
CDCP1 (CUB-domain-containing protein 1) contains three extracellular CUB domains, a transmembrane domain, and two putative cytoplasmic tyrosine phosphorylation sites. Phosphorylation of the gp140 and p80 proteins is mediated by Src family kinases at various tyrosine residues, including Tyr 734. PTP family members mediate the desphosphorylation of CDCP1. The conversion of gp140 to p80 prolongs the phosphorylation state, which may affect signaling in epithelial wounds. CDCP1 acts as a marker for hematopoetic cells and also exhibits high expression in metastatic colon and breast tumors.
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