Product Detail
Product NameATG14L Antibody
Clone No.C10-F7
Host SpeciesMouse
ClonalityMonoclonal
PurificationProA affinity purified
ApplicationsWB, IHC
Species ReactivityHu
Immunogen DescRecombinant protein
ConjugateUnconjugated
Other Names1110038I05Rik antibody
AI314632 antibody
Aldehyde dehydrogenase 6 family member A1 antibody
Aldehyde dehydrogenase family 6 member A1 antibody
Aldehyde dehydrogenase family 6, subfamily A1 antibody
ALDH6A1 antibody
Malonate semialdehyde dehydrogenase antibody
Malonate-semialdehyde dehydrogenase [acylating] antibody
Methylmalonate semialdehyde dehydrogenase [acylating] mitochondrial antibody
Methylmalonate-semialdehyde dehydrogenase [acylating] antibody
MGC37325 antibody
MGC40271 antibody
Mitochondrial acylating methylmalonate semialdehyde dehydrogenase antibody
mitochondrial antibody
MMSA_HUMAN antibody
MMSADHA antibody
MMSDH antibody
Accession NoSwiss-Prot#:Q6ZNE5
Uniprot
Q6ZNE5
Gene ID
22863;
Calculated MW55 KDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:2,000
IHC: 1:50-1:200
Western blot analysis of ATG14L on human ATG14L recombinant protein using anti-ATG14L antibody at 1/1,000 dilution.
Western blot analysis of ATG14L on HEK293 (1) and ATG14L-hIgGFc transfected HEK293 (2) cell lysate using anti-ATG14L antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded human ?testis tissues using anti-ATG14L antibody. Counter stained with hematoxylin.
Required for both basal and inducible autophagy. Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine. Promotes BECN1 translocation from the trans-Golgi network to autophagosomes. Enhances PIK3C3 activity in a BECN1-dependent manner.
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Yes
