Product Detail
Product NameETV5 Antibody
Clone No.C10-H3
Host SpeciesMouse
ClonalityMonoclonal
PurificationProA affinity purified
ApplicationsWB
Species ReactivityHu, Ms
Immunogen DescRecombinant protein
ConjugateUnconjugated
Other NamesERM antibody
Ets related protein ERM antibody
ETS translocation variant 5 antibody
Ets variant gene 5 antibody
Ets-related protein ERM antibody
ETV5 antibody
ETV5_HUMAN antibody
Accession NoSwiss-Prot#:P41161
Uniprot
P41161
Gene ID
2119;
Calculated MW58 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:1,000
Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes includes Ets-1, Ets-2, Erg-1-3, Elk-1, Elf-1, Elf-5, NERF, PU.1, PEA3, ERM, FEV, ER8l, Fli-1, TEL, Spi-B, ESE-1, ESE-3A, Net, ABT1 and ERF. Members of the Ets gene family share a highly conserved carboxy terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. This conserved domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA binding activity of all members of the Ets gene family. Several of these proteins have been shown to recognize similar motifs in DNA that share a centrally located 5'-GGAA-3' element.
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