Product Detail
Product NameTGFBR3 Antibody
Clone No.H11-C5
Host SpeciesMouse
ClonalityMonoclonal
PurificationProA affinity purified
ApplicationsWB
Species ReactivityHu, Ms
Immunogen DescRecombinant protein
ConjugateUnconjugated
Other NamesBeta glycan antibody
Betaglycan antibody
Betaglycan proteoglycan antibody
BGCAN antibody
TGBR3_HUMAN antibody
TGF beta receptor type 3 antibody
TGF beta receptor type III antibody
TGF-beta receptor type 3 antibody
TGF-beta receptor type III antibody
TGFB R3 antibody
TGFBR 3 antibody
TGFBR3 antibody
TGFR 3 antibody
TGFR-3 antibody
TGFR3 antibody
Transforming growth factor beta receptor III antibody
Transforming growth factor beta receptor III betaglycan 300kDa antibody
Transforming growth factor beta receptor type 3 antibody
Accession NoSwiss-Prot#:Q03167
Uniprot
Q03167
Gene ID
7049;
Calculated MW93 kDa
Formulation1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:2,000
A total of three members of the TGFβ family, TGFβ1, TGFβ2 and TGFβ3, have been identified in mammals. Each is synthesized as a latent precursor that is subsequently cleaved forming the 112 amino acid growth factor which becomes active upon dimerization. TGFβs mediate their activity by high affinity binding to the type II receptor transmembrane protein with a cytoplasmic serine-threonine kinase domain. TGFβ RIII (transforming growth factor beta receptor type 3), also known as TGFBR3 or TGFR-3, is an 850 amino acid secreted and single-pass type I membrane protein that contains one ZP domain and may assist in capturing TGFβ for presentation to signaling receptors. TGFβ RIII undergoes post-translational modification by glycosaminoglycan groups (GAG) and is encoded by a gene that maps to human chromosome 1p22.2.
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