Product Detail
Product NameSCGB2A2 Antibody
Clone No.E2-C80
Host SpeciesMouse
ClonalityMonoclonal
PurificationProA affinity purified
ApplicationsWB,ICC,IHC,FC
Species ReactivityHu
Immunogen DescRecombinant protein
ConjugateUnconjugated
Other NamesMammaglobin 1 antibody
Mammaglobin-1 antibody
Mammaglobin-A antibody
MGB1 antibody
Scgb2a2 antibody
Secretoglobin family 2A member 2 antibody
SG2A2 antibody
SG2A2_HUMAN antibody
UGB2 antibody
Accession NoSwiss-Prot#:Q13296
Uniprot
Q13296
Gene ID
4250;
Calculated MW11 kDa
Formulation1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:1,000
IHC: 1:50-1:200
ICC: 1:50-1:200
FC: 1:100-1:200
Western blot analysis of Mammaglobin A on human Mammaglobin A recombinant protein using anti- Mammaglobin A antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded human mammary cancer tissue using anti- Mammaglobin A antibody. Counter stained with hematoxylin.
ICC staining Mammaglobin A (green) and actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Flow cytometric analysis of SK-BR-3 cells with Mammaglobin A antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; purple).
Secretoglobins (also called lipophilins or mammaglobins) are small secreted proteins of endocrine-responsive organs and mucosal epithelia that form multimeric complexes and correlate with the development of various human cancers. Lipophilin A and Lipophilin B are orthologs of prostatein (estramustine-binding protein), the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin A, also designated LIPA, LPHA and secretoglobin, family 1D, member 1 (SCGB1D1), is a component of a heterodimeric molecule present in human tears. Lipophilin B, also designated LIPB, LPHB and secretoglobin, family 1D, member 2 (SCGB1D2), mRNA can be overexpressed in breast tumors and shows a high degree of correlation with the mRNA expression profile of mammaglobin. Histological detection in breast tissue of Mammaglobin A, also designated MGB1 and secretoglobin, family 2A, member 2 (SCGB2A2) and Mammaglobin B (also designated MGB2, lipophilin C, LPHC, UGB3 and SCGB2A2) is a reliable diagnostic marker for breast tumors.
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