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LPA Antibody#48474

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Product Detail

Product NameLPA Antibody

Clone No.B6-H1

Host SpeciesMouse

ClonalityMonoclonal

PurificationAffinity purification

ApplicationsWB;IHC;IF

Species ReactivityHu

Immunogen DescPurified recombinant fragment of ApoA

ConjugateUnconjugated

Other NamesAK38 antibody
Antiangiogenic AK38 protein antibody
apo(a) antibody
APOA antibody
apolipoprotein(a) antibody
LP antibody
lp(a) antibody
LPA antibody

Accession NoSwiss-Prot#:P08519

Uniprot P08519

Calculated MW501 kDa

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

StorageStore at -20˚C

Application Details
WB 1:500 - 1:2000;
IHC 1:200 - 1:1000;
IF 1:50 - 1:200
Western blot analysis of Lipoprotein a on human Lipoprotein a recombinant protein using anti- Lipoprotein a antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti- Lipoprotein a antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti- Lipoprotein a antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human rectum cancer tissue using anti- Lipoprotein a antibody. Counter stained with hematoxylin.
ICC staining Lipoprotein a (green) and actin filaments (red) in HepG2 cell. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

The protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I. The encoded protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis. Elevated plasma levels of this protein are linked to atherosclerosis. Depending on the individual, the encoded protein contains 2-43 copies of kringle-type domains. The allele represented here contains 15 copies of the kringle-type repeats and corresponds to that found in the reference genome sequence.

If you have published an article using product 48474, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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