Product Detail
Product NameFUK Antibody
Clone No.E2-C3
Host SpeciesMouse
ClonalityMonoclonal
PurificationProA affinity purified
ApplicationsWB,FC
Species ReactivityHu, Ms, Rt, Monkey
Immunogen DescRecombinant protein
ConjugateUnconjugated
Accession NoSwiss-Prot#:Q8N0W3
Uniprot
Q8N0W3
Gene ID
197258;
Calculated MW117 kDa, additional band 42kDa
Formulation1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:1,000
FC: 1:100-1:200
Western blot analysis of Fucokinase on different cell lysates using anti- Fucokinase antibody at 1/1,000 dilution.
Positive control:
Lane 1: Hela
Lane 2: HepG2
Lane 3: Jurkat
Lane 4: A431
Lane 5: HEK293
Lane 6: MCF-7
Lane 7: PC-12
Lane 8: Cos7
Lane 9:NIH/3T3
Flow cytometric analysis of Hela cells with Fucokinase antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; purple).
The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date.
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