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BDNF Antibody#48503

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Product Detail

Product NameBDNF Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationPeptide affinity purified

ApplicationsWB, ICC, IHC

Species ReactivityHu, Ms, Rt

Immunogen DescThis antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to the N-terminal of human BNDF

ConjugateUnconjugated

Other NamesAbrineurin antibody
ANON2 antibody
BDNF antibody
BDNF_HUMAN antibody
Brain Derived Neurotrophic Factor antibody
Brain-derived neurotrophic factor antibody
BULN2 antibody
MGC34632 antibody
Neurotrophin antibody

Accession NoSwiss-Prot#:P23560

Uniprot P23560

Gene ID 627;

Calculated MW28kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:500
IHC: 1:200
ICC: 1:200

Western blot analysis of BDNF on different cell lysates using anti-BDNF antibody at 1/500 dilution.

Positive control:

Lane 1: A172

Lane 2: SHG-44

Lane3: Mouse heart

Lane 4: Mouse brain

Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-BDNF antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-BDNF antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-BDNF antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-BDNF antibody. Counter stained with hematoxylin.
ICC staining of BNDF in SHG-44 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Brain-derived neurotrophic factor, also known as BDNF, is a member of the "neurotrophin" family of growth factors, which are related to the canonical "Nerve Growth Factor", NGF. BDNF acts on certain neurons of the central nervous system and the peripheral nervous system, helping to support the survival of existing neurons, and encourage the growth and differentiation of new neurons and synapses. BDNF is actually found in a range of tissue and cell types, not just in the brain. It is also expressed in the retina, the central nervous system, motor neurons, the kidneys, and the prostate. Various studies have shown possible links between BDNF and conditions such as depression, bipolar disorder,schizophrenia, obsessive-compulsive disorder, Alzheimer's disease, Huntington's disease, Rett syndrome, and dementia, as well as anorexia nervosa and bulimia nervosa.

If you have published an article using product 48503, please notify us so that we can cite your literature.

et al,Classical prescription Daqinjiao decoction inhibit cerebral ischemia/reperfusion induced necroptosis and ferroptosis through multiple mechanisms. , (2025),
PMID: 39736347

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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