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VDAC1 Rabbit mAb#48607

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Product Detail

Product NameVDAC1 Rabbit mAb

Clone No.SA93-03

Host SpeciesRecombinant Rabbit

ClonalityMonoclonal

PurificationProA affinity purified

ApplicationsWB, IHC

Species ReactivityHu, Ms, Rt

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesN2441 antibody
OMP2 antibody
POR1 antibody
hVDAC1 antibody
MGC111064 antibody
Mitochondrial Porin antibody
Outer mitochondrial membrane protein porin 1 antibody
Plasmalemmal porin antibody
Porin 31HL antibody
Porin 31HM antibody
VDAC antibody
VDAC-1 antibody
Vdac1 antibody
VDAC1_HUMAN antibody
Voltage dependent anion channel 1 antibody
Voltage dependent anion selective channel protein 1 antibody
Voltage-dependent anion-selective channel protein 1 antibody
YNL055C antibody
YNL2441C antibody

Accession NoSwiss-Prot#:P21796

Uniprot P21796

Gene ID 7416;

Calculated MW31 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000-5,000
IHC: 1:50-1:200


Western blot analysis of VDAC1 on different cell lysates using anti-VDAC1 antibody at 1/1,000 dilution. Positive control:
Lane 1: Raji
Lane 2: HepG2
Lane 3: SW480
Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-VDAC1 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-VDAC1 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-VDAC1 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-VDAC1 antibody. Counter stained with hematoxylin.
Voltage-dependent anion-selective channel (VDAC1) (also referred to as porin, isoform 1) is a small protein, originally discovered in the outer membrane of mitochondria where it constitutes the major pore-forming protein. The porin protein VDAC1 allows to the outer-most membrane of the mitochondrion free permeability to low molecular-weight solutes. VDAC1 has been shown to co-immunoprecipitate with the anti-apoptotic protein Bcl-2 and suggested to be involved in forming the mitochondrial pore which releases cytochrome c during apoptosis.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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