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Scavenging Receptor SR-BI Rabbit mAb#48651

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Product NameScavenging Receptor SR-BI Rabbit mAb

Clone No.SR37-06

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, ICC, IHC, FC

Species ReactivityHu, Ms, Rt

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesCD36 and LIMPII analogous 1 antibody
CD36 antibody
CD36 Antigen like 1 antibody
CD36 antigen-like 1 antibody
CD36L1 antibody
CLA 1 antibody
CLA-1 antibody
CLA1 antibody
Collagen type I receptor antibody
HDLQTL6 antibody
MGC138242 antibody
SCARB1 antibody
Scavebger Receptor Class B Member 1 antibody
Scavenger receptor class B member 1 antibody
Scavenger Receptor Class B Type 1 antibody
SCRB1_HUMAN antibody
SR BI antibody
SR-BI antibody
SRB1 antibody
SRBI antibody
Thrombospondin receptor like 1 antibody
thrombospondin receptor-like 1 antibody

Accession NoSwiss-Prot#:Q8WTV0

Uniprot Q8WTV0

Gene ID 949;

Calculated MW80 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000-5,000
IHC: 1:50-1:200
ICC: 1:50-1:200

FC: 1:50-1:200
Western blot analysis of Scavenging Receptor SR-BI on different lysates using anti-Scavenging Receptor SR-BI antibody at 1/1,000 dilution. Positive control:
Lane 1: Human liver
Lane 2: Mouse liver
Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Scavenging Receptor SR-BI antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-Scavenging Receptor SR-BI antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-Scavenging Receptor SR-BI antibody. Counter stained with hematoxylin.
ICC staining Scavenging Receptor SR-BI in CRC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining Scavenging Receptor SR-BI in PC-12 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
The macrophage class A scavenger receptors (SR-A) type I and II mediate the uptake of modified low density lipoprotein (LDL), while the scavenger receptor class B type 1 (SR-B1) mediates the selective uptake of cholesterol and cholesterol esters (CE) from HDLs into cells. SREC, Ox-LDL-R1, SR-A and SR-B1 may all be involved in the early development of atherosclerosis. SR-B1, an integral membrane protein, acts as a receptor for various ligands, including apoptotic cells, cholesterol ester, phospholipids, lipoproteins and phosphatidyl-serine. SR-B1, which may be involved in phagocytosis of apoptotic cells, enables the movement of cholesterol between the cell surface and extracellular donors and acceptors. Although it is widely expressed, SR-B1 localizes primarily to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae.

If you have published an article using product 48651, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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