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Location： Home > Recombinant Rabbit Monoclonal Antibodies > p16 ARC Rabbit mAb

p16 ARC Rabbit mAb#48673

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Product Detail

Product Namep16 ARC Rabbit mAb

Clone No.SR34-02

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, ICC/IF, IHC, IP, FC

Species ReactivityHu, Ms, Rt

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesActin related protein 2/3 complex subunit 5 (16 kD) antibody
Actin related protein 2/3 complex subunit 5 antibody
Actin related protein 2/3 complex, subunit 5 16kDa antibody
Actin-related protein 2/3 complex subunit 5 antibody
ARC16 antibody
Arp2/3 complex 16 kDa subunit antibody
Arp2/3 protein complex subunit p16 antibody
ARPC 5 antibody
Arpc5 antibody
ARPC5_HUMAN antibody
dJ127C7.3 antibody
MGC88523 antibody
p16 Arc antibody
p16-ARC antibody
RP1 127C7.3 antibody

Accession NoSwiss-Prot#:O15511

Uniprot O15511

Gene ID 10092;

Calculated MW16 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000-1:2,000
IHC: 1:50-1:200
ICC: 1:50

FC: 1:50-1:100
Western blot analysis of p16 ARC on different cell lysates using anti-p16 ARC antibody at 1/1,000 dilution. Positive control:
Lane 1: MCF-7
Lane 2: SK-BR-3
Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-p16 ARC antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-p16 ARC antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse spleen tissue using anti-p16 ARC antibody. Counter stained with hematoxylin.
ICC staining p16 ARC in N2A cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Flow cytometric analysis of SH-SY-5Y cells with p16 ARC antibody at 1/50 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as secondary antibody.
The Arp2/3 (Actin-related protein 2/3) complex consists of seven subunits, all of which are actin-related proteins. The complex is involved in the control of actin polymerization and in mediating the formation of branched actin networks. p16-ARC, also known as ARPC5 (Actin-related protein 2/3 complex subunit 5) or ARC16 (Arp2/3 complex 16 kDa subunit), is a 151 amino acid subunit of the Arp2/3 complex. Thought to play a role in maintaining the integrity of Arp2/3, p16-ARC is a substrate for MAPKAPK-2 which, through phosphorylation of p16-ARC, may participate in Arp2/3 regulatory functions and remodeling of the Actin cytoskeleton. Two isoforms of p16-ARC exist due to alternative splicing events.

If you have published an article using product 48673, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
;

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