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Tau Rabbit mAb#48681

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Product Detail

Product NameTau Rabbit mAb

Clone No.SZ03-03

ClonalityMonoclonal

PurificationProA affinity purified

ApplicationsWB, IHC, IP

Species ReactivityHu, Ms, Rt

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesAI413597 antibody
AW045860 antibody
DDPAC antibody
FLJ31424 antibody
FTDP 17 antibody
G protein beta1/gamma2 subunit interacting factor 1 antibody
MAPT antibody
MAPTL antibody
MGC134287 antibody
MGC138549 antibody
MGC156663 antibody
Microtubule associated protein tau antibody
Microtubule associated protein tau isoform 4 antibody
Microtubule-associated protein tau antibody
MSTD antibody
Mtapt antibody
MTBT1 antibody
MTBT2 antibody
Neurofibrillary tangle protein antibody
Paired helical filament tau antibody
Paired helical filament-tau antibody
PHF tau antibody
PHF-tau antibody
PPND antibody
PPP1R103 antibody
Protein phosphatase 1, regulatory subunit 103 antibody
pTau antibody
RNPTAU antibody
TAU antibody
TAU_HUMAN antibody
Tauopathy and respiratory failure, included antibody

Accession NoSwiss-Prot#:P10636

Uniprot P10636

Gene ID 4137;

Calculated MW79 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details

WB: 1:1,000-5,000
IHC: 1:50-1:200
 

Western blot analysis of Tau on mouse brain lysates using anti-Tau antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-Tau antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Tau antibody. Counter stained with hematoxylin.

Tau, also known as MAPT (microtubule-associated protein tau), MAPTL, MTBT1 or TAU, is a 758 amino acid protein that localizes to the cytoplasm, as well as to the cytoskeleton and the cell membrane, and contains four Tau/MAP repeats. Expressed in neuronal tissue and existing as multiple alternatively spliced isoforms, Tau functions to promote microtubule assembly and stability and is thought to be involved in the maintenance of neuronal polarity. Tau may also link microtubules with neural plasma membrane components and, addition to its role in microtubule stability, is also necessary for cytoskeletal plasticity. Tau is highly subject to a variety of post-translational modifications, including phosphorylation on serine and threonine residues, polyubiquitination (and subsequent proteasomal degradation) and glycation of specific Tau isoforms. Defects in the gene encoding Tau are associated with Alzheimers disease, pallido-ponto-nigral degeneration (PPND), corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP).

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
;

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