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Location： Home > Recombinant Rabbit Monoclonal Antibodies > ATM Rabbit mAb

ATM Rabbit mAb#48744

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Product Detail

Product NameATM Rabbit mAb

Clone No.SI70-01

Host SpeciesRecombinant Rabbit

ClonalityMonoclonal

PurificationProA affinity purified

ApplicationsWB, ICC/IF, IHC

Species ReactivityHu

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesA-T mutated antibody
A-T mutated homolog antibody
AT mutated antibody
AT1 antibody
ATA antibody
Ataxia telangiectasia mutated antibody
Ataxia telangiectasia mutated gene antibody
Ataxia telangiectasia mutated homolog (human) antibody
Ataxia telangiectasia mutated homolog antibody
ATC antibody
ATD antibody
ATDC antibody
ATE antibody
ATM antibody
ATM serine/threonine kinase antibody
ATM_HUMAN antibody
DKFZp781A0353 antibody
MGC74674 antibody
OTTHUMP00000232981 antibody
Serine protein kinase ATM antibody
Serine-protein kinase ATM antibody
Serine/threonine-protein kinase ATM antibody
Tefu antibody
TEL1 antibody
TEL1, telomere maintenance 1, homolog antibody
TELO1 antibody
Telomere fusion protein antibody

Accession NoSwiss-Prot#:Q13315

Uniprot Q13315

Gene ID 472;

Calculated MW350 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000-5,000
IHC: 1:50-1:200
ICC: 1:50-1:200

Western blot analysis of ATM on CRC cell lysates using anti-ATM antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-ATM antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-ATM antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-ATM antibody. Counter stained with hematoxylin.
ICC staining ATM in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining ATM in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining ATM in CRC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
The phosphatidylinositol kinase (PIK) family members fall into two distinct subgroups. The first subgroup contains proteins such as the PI 3- and PI 4-kinases and the second group comprises the PIK-related kinases. The PIK-related kinases include Atm, DNA-PKCS and FRAP. These proteins have in common a region of homology at their carboxy-termini that is not present in the PI 3- and PI 4-kinases. The Atm gene is mutated in the autosomal recessive disorder ataxia telangiectasia (AT) that is characterized by cerebellar degeneration (ataxia) and the appearance of dilated blood vessels (telangiec-tases) in the conjunctivae of the eyes. AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and display delays in p53 induction.

If you have published an article using product 48744, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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