Product Detail
Product NameMMP2 Rabbit mAb
Clone No.SI15-04
Host SpeciesRecombinant Rabbit
ClonalityMonoclonal
PurificationProA affinity purified
ApplicationsWB, IHC
Species ReactivityHu, Ms, Rt
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other Names72 kDa gelatinase antibody 72kD type IV collagenase antibody CLG 4 antibody CLG 4A antibody CLG4 antibody CLG4A antibody Collagenase Type 4 alpha antibody Collagenase type IV A antibody Gelatinase A antibody Gelatinase alpha antibody Gelatinase neutrophil antibody Matrix metallopeptidase 2 gelatinase A 72kDa gelatinase 72kDa type IV collagenase antibody Matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) antibody Matrix Metalloproteinase 2 antibody Matrix metalloproteinase II antibody Matrix metalloproteinase-2 antibody MMP 2 antibody MMP II antibody MMP-2 antibody MMP2 antibody MMP2_HUMAN antibody MONA antibody Neutrophil gelatinase antibody PEX antibody TBE 1 antibody TBE-1 antibody
Accession NoSwiss-Prot#:P08253
Uniprot
P08253
Gene ID
4313;
Calculated MW72 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:1,000-1:2,000
IHC: 1:50-1:200
Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-MMP2 antibody. Counter stained with hematoxylin.
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB) . MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV, V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.
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