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Location： Home > Recombinant Rabbit Monoclonal Antibodies > Plectin Rabbit mAb

Plectin Rabbit mAb#48803

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Product Detail

Product NamePlectin Rabbit mAb

Clone No.SY29-04

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, IHC, IP

Species ReactivityHu, Ms, Rt

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesEBS1 antibody
EBSO antibody
HD1 antibody
Hemidesmosomal protein 1 antibody
PCN antibody
pleC antibody
PLEC_HUMAN antibody
PLEC1 antibody
PLEC1b antibody
Plectin 1 antibody
Plectin 1 intermediate filament binding protein 500kDa antibody
Plectin 6 antibody
Plectin antibody
Plectin-1 antibody
PLTN antibody

Accession NoSwiss-Prot#:Q15149

Uniprot Q15149

Gene ID 5339;

Calculated MW531 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000
IHC: 1:100-1:500


Immunohistochemical analysis of paraffin-embedded rat skeletal muscle tissue using anti-Plectin antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue using anti-Plectin antibody. Counter stained with hematoxylin.
Plectin is an abundant cytoskeletal protein that is involved in cytoplasm stabilization. Plectin has been shown to crosslink intermediate filaments to microtubules and microfilaments, and to anchor intermediate filaments to the plasma and nuclear membranes. Plectin binds both Lamin B and vimentin, and this binding is regulated by a variety of protein kinases. Phosphorylation by PKA or PKC results in decreased binding to Lamin B, and phosphorylation by PKA enhances the plectin-vimentin interactions. Plectin is also a substrate for p34cdc2 kinase. Several alternative splice isoforms of plectin are known to exist. Mutations in human plectin are known to cause epidermolysis bullosa simplex with muscular dystrophy (EBS-MD).

If you have published an article using product 48803, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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