Product Detail
Product NameELK1 Rabbit mAb
Clone No.SU32-05
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, ICC, IP
Species ReactivityHu, Ms, Rt
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other NamesELK 1 antibody Elk1 antibody ELK1 member of ETS oncogene family antibody ELK1 protein antibody ELK1, ETS transcription factor antibody ELK1_HUMAN antibody ELK2 member of ETS oncogene family antibody ETS domain containing protein Elk 1 antibody ETS domain containing protein Elk1 antibody ETS domain protein Elk1 antibody ETS domain-containing protein Elk-1 antibody ETS like gene 1 antibody Member of ETS oncogene family antibody Oncogene Elk1 antibody Tyrosine kinase (ELK1) oncogene antibody
Accession NoSwiss-Prot#:P19419
Uniprot
P19419
Gene ID
2002;
Calculated MW62 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:1,000-1:2,000
ICC: 1:50-1:200
Western blot analysis of ELK1 on human lung lysates using anti-ELK1 antibody at 1/1,000 dilution.
ICC staining ELK1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes Ets-1, Ets-2, Erg-1C3, Elk-1, Elf-1, Elf-5, NERF, PU.1, PEA3, ERM, FEV, ER8l, Fli-1, TEL, Spi-B, ESE-1, ESE-3A, Net, ABT1 and ERF. Members of the Ets gene family exhibit varied patterns of tissue expression, and share a highly conserved carboxy terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. This conserved domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA binding activity of all members of the Ets gene family. Several of these proteins have been shown to recognize similar motifs in DNA that share a centrally located 5'-GGAA-3' element.
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