Product Detail
Product NameSOX18 Rabbit mAb
Clone No.ST43-02
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IHC
Species ReactivityHu, Ms, Rt
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other NamesHLTS antibody SOX 18 antibody Sox18 antibody SOX18_HUMAN antibody SRY (sex determining region Y) box 18 antibody SRY box 18 antibody Transcription factor SOX 18 antibody Transcription factor SOX-18 antibody
Accession NoSwiss-Prot#:P35713
Uniprot
P35713
Gene ID
54345;
Calculated MW41 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:1,000
IHC:1:50-1:200
Western blot analysis of SOX18 on K562 cells lysates using anti-SOX18 antibody at 1/1,000 dilution.
Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. Sox-18 is a 384 amino acid nuclear protein that contains one HMG box DNA-binding domain and belongs to the Sox family of transcriptional regulators.
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