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Location： Home > Recombinant Rabbit Monoclonal Antibodies > Metabotropic glutamate receptor 5 Rabbit mAb

Metabotropic glutamate receptor 5 Rabbit mAb#48873

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Product Detail

Product NameMetabotropic glutamate receptor 5 Rabbit mAb

Clone No.ST51-00

Clonality Monoclonal

PurificationAffinity-chromatography

ApplicationsWB;IHC;ICC/IF;FC

Species ReactivityHu, Ms, Rt

Immunogen DescA synthesized peptide derived from human mGluR5

ConjugateUnconjugated

Other NamesGlutamate receptor metabotropic 5 antibody
GPRC1E antibody
Grm5 antibody
GRM5_HUMAN antibody
Metabotropic glutamate receptor 5 antibody
Metabotropic glutamate receptor 5 variant F antibody
Metabotropic glutamate receptor 5 variant G antibody
Metabotropic glutamate receptor 5 variant H antibody
mGlu5 antibody
mGluR5 antibody
PPP1R86 antibody
Protein phosphatase 1 regulatory subunit 86 antibody

Accession NoSwiss-Prot#:P41594

Uniprot P41594

Gene ID 2915;

Calculated MW132 kDa

FormulationRabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

StorageStore at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Application Details
WB 1:1000-1:2000
IHC 1:100-1:200
ICC/IF 1:50-1:200
FC 1:20-1:100
Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-GRM5 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-GRM5 antibody. Counter stained with hematoxylin.
ICC staining GRM5 in JAR cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining GRM5 in PC12 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining GRM5 in SHG-44 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Flow cytometric analysis of SH-SY-5Y cells with GRM5 antibody at 1/50 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.

If you have published an article using product 48873, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
;

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