Product Detail
Product NameSrc Rabbit mAb
Clone No.ST05-03
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, ICC/IF, IHC
Species ReactivityHu, Rt
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other NamesASV antibody
Avian sarcoma virus antibody
c SRC antibody
CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA antibody
cSrc antibody
EC 2.7.10.2 antibody
Neuronal CSRC tyrosine specific protein kinase antibody
Neuronal SRC antibody
Oncogene SRC antibody
OTTHUMP00000174476 antibody
OTTHUMP00000174477 antibody
p60 Src antibody
p60-Src antibody
p60Src antibody
pp60c src antibody
pp60c-src antibody
pp60csrc antibody
Proto oncogene tyrosine protein kinase Src antibody
Proto-oncogene c-Src antibody
Proto-oncogene tyrosine-protein kinase Src antibody
Protooncogene SRC antibody
Protooncogene SRC Rous sarcoma antibody
Src antibody
SRC Oncogene antibody
SRC proto oncogene non receptor tyrosine kinase antibody
SRC_HUMAN antibody
SRC1 antibody
Tyrosine kinase pp60c src antibody
Tyrosine protein kinase SRC 1 antibody
Tyrosine protein kinase SRC1 antibody
v src avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog antibody
V src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog (avian) antibody
v src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog avian antibody
Accession NoSwiss-Prot#:P12931
Uniprot
P12931
Gene ID
6714;
Calculated MW60 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:1,000
IHC: 1:50-1:200
ICC: 1:50-1:200
Western blot analysis of Src on A431 cell lysates using anti-Src antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded rat testis tissue using anti-Src antibody. Counter stained with hematoxylin.
ICC staining Src in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
The major translational products of the Src gene family are membrane-associated tyrosine protein kinases that lack transmembrane and external amino acid sequences. By virtue of their common structural motifs, the Src family is composed of nine members in vertebrates, including c-Src, c-Yes, Fgr, Yrk, Fyn, Lyn, Hck, Lck and Blk. Src family kinases, which contain an amino-terminal cell membrane anchor followed by SH3 and SH2 domains, transduce signals that are involved in the control of a variety of cellular processes, including proliferation, differentiation, motility and adhesion. Src family members are normally maintained in an inactive state and can be activated transiently during cellular events such as mitosis. Different subcellular locations of Src family kinases may be important for the regulation of specific cellular processes, such as mitogenesis, cytoskeletal organization and membrane trafficking. c-Src (also designated pp60Src, Src p60 and proto-oncogene tyrosine protein kinase Src) is expressed in a broad range of tissue and cell types, although the highest levels of c-Src are detected in neuronal tissues and platelets. c-Src may play a role in events associated with both neuronal differentiation and maintenance of mature neuronal cell functions.
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