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Location： Home > Recombinant Rabbit Monoclonal Antibodies > CD11a Rabbit mAb

CD11a Rabbit mAb#48920

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Product Detail

Product NameCD11a Rabbit mAb

Clone No.SR4524

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, ICC/IF, IHC, IP, FC

Species ReactivityHu

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesLymphocyte function associated antigen, type 1, alpha subunit antibody
Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide antibody
Antigen CD11A antibody
CD 11a antibody
CD11 antigen-like family member A antibody
CD11a antibody
CD11a antigen antibody
Integrin Alpha L antibody
Integrin alpha-L antibody
Integrin gene promoter antibody
Integrin, alpha L (antigen CD11A (p180), lymphocyte function associated antigen 1; alpha polypeptide) antibody
ITAL_HUMAN antibody
Itgal antibody
ITGAL protein antibody
Leukocyte adhesion glycoprotein LFA 1 alpha chain antibody
Leukocyte adhesion glycoprotein LFA-1 alpha chain antibody
Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain antibody
Leukocyte function associated molecule 1 alpha chain antibody
Leukocyte function-associated molecule 1 alpha chain antibody
LFA 1 alpha (LFA1A) antibody
LFA 1 alpha antibody
LFA 1 antibody
LFA 1A antibody
LFA-1A antibody
LFA1A antibody
Ly15 antibody
Ly21 antibody
Lymphocyte function associated antigen 1 antibody
Lymphocyte Function Associated Antigen Type 1 alpha antibody
lymphocyte function-associated antigen 1, alpha polypeptide antibody
p180 antibody

Accession NoSwiss-Prot#:P20701

Uniprot P20701

Gene ID 3683;

Calculated MW180 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000-5,000
IHC: 1:50-1:200
ICC: 1:50-1:200

FC: 1:50-1:100
Western blot analysis of CD11a on Jurkat cell lysates using anti-CD11a antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD11a antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD11a antibody. Counter stained with hematoxylin.
ICC staining CD11a in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining CD11a in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining CD11a in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Flow cytometric analysis of K562 cells with CD11a antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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