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BCL2A1 Rabbit mAb#48932

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Product Detail

Product NameBCL2A1 Rabbit mAb

Clone No.SC05-42

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, IHC, FC

Species ReactivityHu, Ms, Rt

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesACC 1 antibody
ACC 2 antibody
B2LA1_HUMAN antibody
Bcl 2 related protein A1 antibody
Bcl-2-like protein 5 antibody
Bcl-2-related protein A1 antibody
BCL2 related protein A1 antibody
Bcl2-L-5 antibody
BCL2A1 antibody
BCL2L5 antibody
BFL1 antibody
GRS antibody
HBPA1 antibody
Hematopoietic BCL2 related protein A1 antibody
Hemopoietic specific early response protein antibody
Hemopoietic-specific early response protein antibody
Protein BFL 1 antibody
Protein BFL-1 antibody
Protein GRS antibody

Accession NoSwiss-Prot#:Q16548

Uniprot Q16548

Gene ID 597;

Calculated MW20 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000
IHC:1:50-1:200


FC: 1:50-1:100
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-BCL2A1 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti- BCL2A1 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti- BCL2A1 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti- BCL2A1 antibody. Counter stained with hematoxylin.
Flow cytometric analysis of 293 cells with Bfl1(BCL2A1) antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
The Bcl-2 family of proteins is characterized by its ability to modulate cell death under a broad range of physiological conditions. Bcl-2 and Bcl-xL function to inhibit apoptosis while other members of the Bcl-2 family, Bax, Bad, Bak and Bcl-xS, oppose death-suppressing effects. An additional member of the family, A1 (also designated Bfl-1), dimerizes with both Bcl-2 and Bax and has been identified as a hematopoietic- specific, early inducible gene. While A1 demonstrates life promoting properties similar to those of Bcl-2, its function may be more temporally regulated during myeloid differentiation and dependent on additional growth stimuli to confer its life promoting properties. A1 is abundantly expressed in bone marrow and at low levels in other tissues. There is evidence that a correlation exists between a high expression of the A1 gene product and stomach cancer.

If you have published an article using product 48932, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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