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Location： Home > Recombinant Rabbit Monoclonal Antibodies > IKB beta Rabbit mAb

IKB beta Rabbit mAb#49019

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Product Detail

Product NameIKB beta Rabbit mAb

Clone No.SN0648

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, ICC, IHC, IP

Species ReactivityHu

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesI kappa B beta antibody
I-kappa-B-beta antibody
IkappaBbeta antibody
IKB beta antibody
IkB-B antibody
IkB-beta antibody
IKBB antibody
IKBB_HUMAN antibody
IkBbeta antibody
NF kappa BIB antibody
NF-kappa-B inhibitor beta antibody
NF-kappa-BIB antibody
Nfkbib antibody
Thyroid receptor interacting protein 9 antibody
Thyroid receptor-interacting protein 9 antibody
TR interacting protein 9 antibody
TR-interacting protein 9 antibody
TRIP-9 antibody
TRIP9 antibody

Accession NoSwiss-Prot#:Q15653

Uniprot Q15653

Gene ID 4793;

Calculated MW48 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000
IHC: 1:50-1:200
ICC: 1:50-1:200

Western blot analysis of IKB beta on different lysates using anti-IKB beta antibody at 1/1,000 dilution. Positive control:
Lane 1: Jurkat
Lane 2: Hela
Lane 3: THP-1
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-IKB beta antibody. Counter stained with hematoxylin.
ICC staining IKB beta in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining IKB beta in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
On the basis of both functional and structural considerations, members of the IkB family of proteins can be divided into four groups. The first of these groups, IkB-α, includes the avian protein pp40 and the mammalian MAD-3, both of which inhibit binding of p50-p65 NFkB complex or Rel protein to their cognate binding sites but do not inhibit the binding of p50 homodimer to kB sites, suggesting that the IkB-α family binds to the p65 subunit of p50-p65 heterocomplex through ankyrin repeats. The second member of the IkB family is represented by a protein designated IkB-β. The third group of IkB proteins is represented by IkB-ε, which is identical in sequence with the C-terminal domain of the p110 precursor of NFkB p50 and is expressed predominantly in lymphoid cells. An additional IkB family member, IkB-, has several phosphorylated forms and is primarily found complexed with Rel A and/or c-Rel.

If you have published an article using product 49019, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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