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BPI Rabbit mAb#49074

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Product Detail

Product NameBPI Rabbit mAb

Clone No.SN06-63

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, FC

Species ReactivityHu, zebrafish

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesBactericidal permeability-increasing protein antibody
bactericidal/permeability-increasing protein antibody
BPI antibody
BPI fold containing family D, member 1 antibody
BPIFD1 antibody
CAP 57 antibody
rBPI antibody
recombinant BPI holoprotein, rBPI antibody

Accession NoSwiss-Prot#:P17213

Uniprot P17213

Gene ID 671;

Calculated MW57 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000-1:2,000



FC: 1:50-1:100
Western blot analysis of BPI on THP-1 cells lysates using anti-BPI antibody at 1/1,000 dilution.
Flow cytometric analysis of Jurkat cells with BPI antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
The bactericidal permeability increasing protein (BPI) is an antibacterial and endotoxin-neutralizing molecule that is abundant in the granules of polymorphonuclear leukocytes (neutrophil granules). The 31.5-kb-long human BPI gene maps to chromosome 20q11.23-q12, contains 15 exons, and encodes a 456 amino acid protein. Epithelial cells which line mucosal surfaces are the first line of defense against bacterial invasion and infection. BPI localizes to the cell surface of epithelial cells and blocks endotoxin-mediated signaling, thereby protecting mucosal surfaces against gram-negative bacteria and their endotoxin. BPI, lipopolysaccharide binding protein (LBP), phospholipid transfer protein (PLTP), and cholesteryl ester transfer protein (CETP) constitutes a family of functionally related proteins.

If you have published an article using product 49074, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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