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Location： Home > Recombinant Rabbit Monoclonal Antibodies > Bcl10 Rabbit mAb

Bcl10 Rabbit mAb#49095

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Product Detail

Product NameBcl10 Rabbit mAb

Clone No.SN74-04

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, ICC/IF, IHC, IP

Species ReactivityHu

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesAI132454 antibody
B cell CLL/lymphoma 10 antibody
B cell lymphoma/leukemia10 antibody
B-cell CLL/lymphoma 10 antibody
B-cell leukemia/lymphoma 10 antibody
B-cell lymphoma/leukemia 10 antibody
Bcl 10 antibody
Bcl-10 antibody
Bcl10 antibody
BCL10_HUMAN antibody
c E10 antibody
c-E10 antibody
C81403 antibody
CARD containing apoptotic signaling protein antibody
CARD containing molecule enhancing NF kappa B antibody
CARD containing molecule enhancing NF kB antibody
CARD containing molecule enhancing NF-kB antibody
CARD containing molecule enhancing NFkB antibody
CARD containing proapoptotic protein antibody
CARD like apoptotic protein antibody
CARD-containing apoptotic signaling protein antibody
CARD-containing molecule enhancing NF-kappa-B antibody
CARD-containing proapoptotic protein antibody
CARD-like apoptotic protein antibody
CARMEN antibody
Caspase recruiting domain containing protein antibody
caspase-recruiting domain-containing protein antibody
cCARMEN antibody
cE 10 antibody
cE10 antibody
CED 3/ICH 1 prodomain homologous E10 like regulator antibody
CED-3/ICH-1 prodomain homologous E10-like regulator antibody
CED3/ICH1 prodomain homologous E10 like regulator antibody
Cellular E10 antibody
Cellular homolog of vCARMEN antibody
Cellular-E10 antibody
CIPER antibody
CLAP antibody
hCLAP antibody
Mammalian CARD containing adapter molecule E10 antibody
Mammalian CARD-containing adapter molecule E10 antibody
mE 10 antibody
mE10 antibody
R-RCD1 antibody

Accession NoSwiss-Prot#:O95999

Uniprot O95999

Gene ID 8915;

Calculated MW31 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details

WB: 1:1,000
IHC: 1:50-1:200
ICC: 1:50-1:200

Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Bcl10 antibody. Counter stained with hematoxylin.
ICC staining Bcl10 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining Bcl10 in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Bcl10, also designated CIPER, c-CARMEN and mE10, was first identified as a gene truncated or mutated in MALT B cell lymphomas and other tumor types. Bcl10 is homologous to the equine herpesvirus-2 E10 gene and, like E10, it contains an N-terminal caspase recruitment domain (CARD). Expression of Bcl10 has been shown to induce NFκB activation in a NIK-dependent pathway, and research indicates that the CARD domain is essential for this activation; although in a separate study, Bcl10 by itself did not induce JNK or NFκB activation. Overexpression of Bcl10 has been shown to induce apoptosis in a manner dependent on CARD-mediated oligomerization. Bcl10 has also been shown to play a role in processing of caspase-9 to its active dimer. Other studies have shown that Bcl10 is not mutated in many human tumors and lymphomas.

If you have published an article using product 49095, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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