Product Detail
Product NamePAX7 Rabbit mAb
Clone No.SD083-04
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, FC
Species ReactivityHu, Ms, Rt
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other NamesFLJ37460 antibody HUP1 antibody OTTHUMP00000002534 antibody Paired box 7 antibody Paired box gene 7 antibody Paired box homeotic gene 7 antibody Paired box protein Pax-7 antibody Paired domain gene 7 antibody Paired domain gene HuP1 antibody Pax7 antibody PAX7 transcriptional factor antibody PAX7/FKHR fusion gene, included antibody PAX7_HUMAN antibody PAX7B antibody RGD1564360 antibody RMS2 antibody
Accession NoSwiss-Prot#:P23759
Uniprot
P23759
Gene ID
5081;
Calculated MW57 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:1,000
FC: 1:50-1:100
Western blot analysis of PAX7 on Hela cells lysates using anti-PAX7 antibody at 1/1,000 dilution.
Flow cytometric analysis of MCF-7 cells with PAX7 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody
The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).
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