Product Detail
Product NameCDC42EP1 Rabbit mAb
Clone No.SD08-54
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB
Species ReactivityHu
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other Names55 kDa bone marrow stromal/endothelial cell protein antibody Binder of Rho GTPases 5 antibody Bone marrow stromal/endothelial cell protein, 55-KD antibody BORG 5 antibody BORG5 antibody BORG5_HUMAN antibody CDC42 effector protein (Rho GTPase binding) 1 antibody Cdc42 effector protein 1 antibody Cdc42ep1 antibody CEP 1 antibody CEP1 antibody MGC15316 antibody MSE 55 antibody MSE55 antibody OTTHUMP00000028709 antibody Serum constituent protein antibody Serum protein MSE55 antibody
Accession NoSwiss-Prot#:Q00587
Uniprot
Q00587
Gene ID
11135;
Calculated MW60 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:1,000-1:2,000
Western blot analysis of CDC42EP1 on different lysates using anti-CDC42EP1 antibody at 1/1,000 dilution. Positive control: Lane 1: HUVEC Lane 2: Hela
MSE55 also known as Borg5 or binder of Rho GTPases 5 is a Cdc42 effector protein that induces long cellular extensions in fibroblasts. MSE55 also increases and mediates actin cytoskeleton reorganization at the plasma membrane. MSE55 is a nonkinase CRIB (Cdc42/Rac interactive-binding) domain-containing molecule. An intact CRIB domain is required for the GTP-dependent binding of MSE55 to Cdc42. MSE55 is expressed in a tissue-specific manner in endothelial and bone marrow stromal cells. MSE55 may have a functional role in hematopoiesis or as a negative regulator of Rho GTPase signaling.
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