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Location： Home > Recombinant Rabbit Monoclonal Antibodies > Transferrin Receptor (CD71) Rabbit mAb

Transferrin Receptor (CD71) Rabbit mAb#49320

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Product Detail

Product NameTransferrin Receptor (CD71) Rabbit mAb

Clone No.SR4536

Host SpeciesRecombinant Rabbit

ClonalityMonoclonal

PurificationProA affinity purified

ApplicationsWB;IP;FC

Species ReactivityHu, Ms, Rt

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesCD 71 antibody
CD71 antibody
CD71 antigen antibody
IMD46 antibody
OTTHUMP00000208523 antibody
OTTHUMP00000208524 antibody
OTTHUMP00000208525 antibody
p90 antibody
sTfR antibody
T9 antibody
TFR 1 antibody
TfR antibody
TfR1 antibody
TFR1_HUMAN antibody
TFRC antibody
TR antibody
Transferrin receptor (p90 CD71) antibody
Transferrin receptor protein 1, serum form antibody
Trfr antibody

Accession NoSwiss-Prot#:P02786

Uniprot P02786

Gene ID 7037;

Calculated MW85 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000-1:2,000
IHC: 1:50-1:200


FC: 1:50-1:100
Western blot analysis of Transferrin Receptor on mouse placenta lysates using anti-Transferrin Receptor antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-Transferrin Receptor antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-Transferrin Receptor antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Transferrin Receptor antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse placenta tissue using anti-Transferrin Receptor antibody. Counter stained with hematoxylin.
Flow cytometric analysis of Hela cells with Transferrin Receptor antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody
CD71, also known as the transferrin receptor (TFR), is a type II membrane glycoprotein that exists as a disulfide-linked homodimer of two identical subunits. CD71 binds to two molecules of transferrin and a serum iron-transport protein, and directs the cellular uptake of iron via receptor-mediated endocytosis. CD71 is expressed, typically at high levels, on all proliferating cells, reticulocytes and erythroid precursors. It is not expressed on resting leukocytes, but is upregulated upon activation of lymphocytes, monocytes and macrophages. CD71 is also found on most dividing cells and on brain endothelium. A second transferrin receptor, TFR2, also mediates the uptake of transferrin-bound iron. TFR2 is a two-subunit homodimer and is highly expressed in liver as well as in hepatocytes and erythroid precursors. Mutations in the TFR2 gene result in hereditary hemochromatosis type III (HFE3), an iron overloading disorder predominant in Caucasians.

If you have published an article using product 49320, please notify us so that we can cite your literature.

et al,Ditan Decoction ameliorates vascular dementia-induced cognitive dysfunction through anti-ferroptosis via the HIF1α pathway: Integrating network pharmacology and experimental validation. , (2025),
PMID: 39978449

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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