Product Detail
                                
                                                                        Product NameGlucagon Rabbit mAb
                                        Clone No.JF0960
                                         Host SpeciesRecombinant Rabbit
                                         Clonality Monoclonal
                                                                                PurificationProA affinity purified
                                        ApplicationsWB, IHC
                                        Species ReactivityHu, Ms, Rt
                                                                                                                         Immunogen Descrecombinant protein
                                                                                 ConjugateUnconjugated
                                                                                 Other NamesGCG antibody
                                        Accession NoSwiss-Prot#:P01275
                                        Uniprot
                                        P01275
                                        
                                        Gene ID
                                        2641;
                                        
                                        Calculated MW21 kDa
                                                                                                                         Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
                                        StorageStore at -20˚C
                                                                                                                                                         
                                Application Details
                                WB: 1:500-1:1000
IHC: 1:50-1:200
                             
                            
                                                                
                                    
                                    Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-Glucagon antibody. Counter stained with hematoxylin.
                                 
                                                                
                                    
                                    Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue using anti-Glucagon antibody. Counter stained with hematoxylin.
                                 
                                                             
                            
                                Glucagon is a pancreatic hormone that functions as an antagonist to insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels. Glucagon-like peptide-1 (GLP-1), Glucagon-like peptide-2 (GLP-2), VIP (vasoactive intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are members of the glucagon family of hormones. GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior, whereas GLP-2 is a stimulator of intestinal epithelial growth. VIP causes vasodilation resulting in the lowering of blood pressure. PACAP is abundant in the hypothalamus and has been shown to increase the synthesis of several hormones, including growth hormone.
                            
                            
                                If you have published an article using product 49334, please notify us so that we can cite your literature.
                                                                                                    
                                      et al,Pathophysiological characterization of the ApoE-/-;db/db mouse: A model of diabetes and atherosclerosis.
 ,  (2025),
PMID:
                                    39761864