Product Detail
Product NameTGN46 Rabbit mAb
Clone No.JF1-024
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IHC, IP
Species ReactivityHu
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other NamesTGN 46 antibody TGN 51 antibody TGN38 antibody TGN38 homolog antibody TGN46 antibody TGN48 antibody TGN51 antibody TGOLN2 antibody TGON2_HUMAN antibody Trans Golgi network integral membrane protein 2 antibody Trans golgi network protein 2 antibody Trans Golgi network protein TGN51 antibody Trans-Golgi network integral membrane protein 2 antibody Trans-Golgi network protein TGN51 antibody TTGN2 antibody
Accession NoSwiss-Prot#:O43493
Uniprot
O43493
Gene ID
10618;
Calculated MW95 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:1,000-1:2,000
IHC: 1:50-1:200
IP: 1:50-1:100
Western blot analysis of TGN46 on NIH/3T3 cells lysates using anti-TGN46 antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-TGN46 antibody. Counter stained with hematoxylin.
TGN38 (trans-Golgi network protein 2) is a type I integral membrane protein that constitutively cycles between the TGN and plasma membrane where it partitions nascent proteins into carrier vesicles for transport to appropriate destinations in the cell. The cytosolic domain of TGN38 interacts with AP2 Clathrin adaptor complexes via the tyrosine-containing motif (SDYQRL) to direct internalization from the plasma membrane. N- and O-linked oligosaccharide chains attach to the core TGN38 protein to produce a protein present in brain, lung and kidney.
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