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TGN46 Rabbit mAb#49370

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Product Detail

Product NameTGN46 Rabbit mAb

Clone No.JF1-024

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, IHC, IP

Species ReactivityHu

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesTGN 46 antibody
TGN 51 antibody
TGN38 antibody
TGN38 homolog antibody
TGN46 antibody
TGN48 antibody
TGN51 antibody
TGOLN2 antibody
TGON2_HUMAN antibody
Trans Golgi network integral membrane protein 2 antibody
Trans golgi network protein 2 antibody
Trans Golgi network protein TGN51 antibody
Trans-Golgi network integral membrane protein 2 antibody
Trans-Golgi network protein TGN51 antibody
TTGN2 antibody

Accession NoSwiss-Prot#:O43493

Uniprot O43493

Gene ID 10618;

Calculated MW95 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000-1:2,000
IHC: 1:50-1:200

IP: 1:50-1:100
Western blot analysis of TGN46 on NIH/3T3 cells lysates using anti-TGN46 antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-TGN46 antibody. Counter stained with hematoxylin.
TGN38 (trans-Golgi network protein 2) is a type I integral membrane protein that constitutively cycles between the TGN and plasma membrane where it partitions nascent proteins into carrier vesicles for transport to appropriate destinations in the cell. The cytosolic domain of TGN38 interacts with AP2 Clathrin adaptor complexes via the tyrosine-containing motif (SDYQRL) to direct internalization from the plasma membrane. N- and O-linked oligosaccharide chains attach to the core TGN38 protein to produce a protein present in brain, lung and kidney.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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