Product Detail
Product NameGLP1 Rabbit mAb
Clone No.JF33-10
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, ICC/IF, IHC
Species ReactivityHu
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other NamesGCG antibody glicentin-related polypeptide antibody GLP-1 antibody GLP-1(7-36) antibody GLP-1(7-37) antibody GLP-2 antibody GLP1 antibody GLP1, included antibody GLP2 antibody GLP2, included antibody GLUC_HUMAN antibody Glucagon antibody Glucagon like peptide 1 antibody glucagon-like peptide 1 antibody Glucagon-like peptide 1, included antibody Glucagon-like peptide 2 antibody Glucagon-like peptide 2, included antibody GRPP antibody OXM antibody OXY antibody preproglucagon antibody
Accession NoSwiss-Prot#:P01275
Uniprot
P01275
Gene ID
2641;
Calculated MW21/8/4 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1;500-1:1,000
IHC: 1:50-1:200
ICC: 1:50-1:200
Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-GLP1 antibody. Counter stained with hematoxylin.
ICC staining GLP1 in PC-12 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining GLP1 in SW480 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Glucagon is a pancreatic hormone that functions as an antagonist to insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels. Glucagon-like peptide-1 (GLP-1), Glucagon-like peptide-2 (GLP-2), VIP (vasoactive intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are members of the Glucagon family of hormones. GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior, whereas GLP-2 is a stimulator of intestinal epithelial growth. VIP causes vasodilation resulting in the lowering of blood pressure. PACAP is abundant in the hypothalamus and has been shown to increase the synthesis of several hormones, including growth hormone.
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