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Ctip2 Rabbit mAb#49390

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Product Detail

Product NameCtip2 Rabbit mAb

Clone No.JF09-90

Host SpeciesRecombinant Rabbit

ClonalityMonoclonal

PurificationProA affinity purified

ApplicationsWB, ICC, IHC, FC

Species ReactivityHu

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesATL1 alpha antibody
ATL1 antibody
ATL1 beta antibody
ATL1 gamma antibody
ATL1-delta antibody
B cell CLL/lymphoma 11B/T cell receptor delta constant region fusion protein antibody
B cell lymphoma/leukemia 11B antibody
B-cell CLL/lymphoma 11B (zinc finger protein) antibody
B-cell CLL/lymphoma 11B antibody
B-cell lymphoma/leukemia 11B antibody
BC11B_HUMAN antibody
BCL-11B antibody
Bcl11b antibody
BCL11B/TRDC fusion antibody
COUP TF interacting protein 2 antibody
COUP-TF interacting protein 2 antibody
COUP-TF-interacting protein 2 antibody
Ctip 2 antibody
CTIP-2 antibody
CTIP2 antibody
hRIT1 alpha antibody
hRit1 antibody
Radiation induced tumor suppressor gene 1 antibody
Radiation induced tumor suppressor gene 1 protein antibody
Radiation-induced tumor suppressor gene 1 protein antibody
Rit 1 antibody
Rit1 antibody
zinc finger protein hRit1 alpha antibody
ZNF856B antibody

Accession NoSwiss-Prot#:Q9C0K0

Uniprot Q9C0K0

Gene ID 64919;

Calculated MW100/110kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details

WB: 1:1,000
IHC: 1:50-1:200
ICC: 1:50-1:200

FC: 1:50-1:100

Western blot analysis of Ctip2 on THP-1 cells lysates using anti-Ctip2 antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Ctip2 antibody. Counter stained with hematoxylin.
ICC staining Ctip2 in LO2 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Flow cytometric analysis of Jurkat cells with Ctip2 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody

Bcl-11a (CtIP-1, EVI9, B cell chronic lymphocytic leukemia (CLL)/lymphoma 11A) and Bcl-11b (CtIP-2, RIT1, B cell CLL/lymphoma 11B) genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.

If you have published an article using product 49390, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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