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PGP9.5 Rabbit mAb#49397

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Product Detail

Product NamePGP9.5 Rabbit mAb

Clone No.JF93-08

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, ICC/IF, IHC, IP

Species ReactivityHu, Ms, Rt

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesEpididymis luminal protein 117 antibody
Epididymis secretory protein Li 53 antibody
HEL 117 antibody
HEL S 53 antibody
NDGOA antibody
Neuron cytoplasmic protein 9.5 antibody
OTTHUMP00000218137 antibody
OTTHUMP00000218139 antibody
OTTHUMP00000218140 antibody
OTTHUMP00000218141 antibody
Park 5 antibody
PARK5 antibody
PGP 9.5 antibody
PGP9.5 antibody
PGP95 antibody
Protein gene product 9.5 antibody
Ubiquitin C terminal esterase L1 antibody
Ubiquitin C terminal hydrolase antibody
Ubiquitin C terminal hydrolase L1 antibody
Ubiquitin carboxyl terminal esterase L1 antibody
Ubiquitin carboxyl terminal hydrolase isozyme L1 antibody
Ubiquitin carboxyl-terminal hydrolase isozyme L1 antibody
Ubiquitin thioesterase L1 antibody
Ubiquitin thiolesterase antibody
Ubiquitin thiolesterase L1 antibody
UCH-L1 antibody
UCHL1 antibody
UCHL1_HUMAN antibody

Accession NoSwiss-Prot#:P09936

Uniprot P09936

Gene ID 7345;

Calculated MW25 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:500-1:1000
IHC: 1:50-1:200
ICC: 1:100-1:500
IP: 1:50-1:100
Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-PGP9.5 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-PGP9.5 antibody. Counter stained with hematoxylin.
ICC staining PGP9.5 in PC-3M cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining PGP9.5 in Hela cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining PGP9.5 in PC-12 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
UCH-L1 (ubiquitin C-terminal hydrolase) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCH-L1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. UCH-L1 is expressed in brain neurons. Examination of specific brain regions reveals expression in all areas tested, particularly in the substantia nigra. UCH-L1 represents 1-2% of total soluble brain protein. Its occurrence in Lewy bodies and its function in the proteasome pathway make it a compelling candidate gene in Parkinson disease. The gene which encodes UCH-L1 maps to human chromosome 4p13. The 230 amino acid human UCH-L3 protein is 54% identical to that of UCH-L1. UCH-L3 is the predominant thiol protease and has high-affinity binding sites for ubiquitin.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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