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Location： Home > Recombinant Rabbit Monoclonal Antibodies > IgA Rabbit mAb

IgA Rabbit mAb#49423

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Product Detail

Product NameIgA Rabbit mAb

Clone No.JM10-42

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, ICC/IF, IHC, IP

Species ReactivityHu

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesHepatocellular carcinoma-associated protein TB6 antibody
Ig alpha 1 chain C region antibody
Ig alpha 2 chain C region antibody
IGHA antibody
IGHA1 antibody
IGHA2 antibody
Immunoglobulin heavy constant alpha 1 antibody
Immunoglobulin heavy constant alpha 2 A2m marker antibody
Immunoglobulin heavy constant alpha 2 antibody
PIgR antibody
Poly-Ig receptor antibody
polymeric immunoglobulin receptor antibody
polymeric immunoglobulin receptor Secretory component antibody

Accession NoSwiss-Prot#:P01876

Uniprot P01876

Calculated MW60 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000
IHC: 1:50-1:200
ICC: 1:50-1:200
IP: 1:50-1:100
Western blot analysis of IgA on human plasma lysates using anti-IgA antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-IgA antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-IgA antibody. Counter stained with hematoxylin.
ICC staining IgA in HepG2 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through interchain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin A (IgA) is the main protein of the mucosal immune system. It is generated by B cells in gut-associated lymphoid tissues. Daily production of IgA exceeds that of any of the other immunoglobulins. The IgA heavy chain is an α-chain, and the light chains are either κ- or λ- chains. IgA exists mainly in dimers but can also exist as polymers or as monomers. Dimers and polymers contain a joining (J) chain that can be bound by the polymeric immunoglobulin receptor (pIgR) for transportation of the molecule to mucosal surfaces.

If you have published an article using product 49423, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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