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Location： Home > Recombinant Rabbit Monoclonal Antibodies > Laminin beta 1 Rabbit mAb

Laminin beta 1 Rabbit mAb#49427

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Product Detail

Product NameLaminin beta 1 Rabbit mAb

Clone No.JM099-03

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, IHC, FC

Species ReactivityHu, Ms, Rt

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesCLM antibody
Cutis laxa with marfanoid phenotype antibody
LAM B1 antibody
LAMB 1 antibody
LAMB1 antibody
LAMB1_HUMAN antibody
Laminin B1 antibody
Laminin B1 chain antibody
Laminin beta 1 chain antibody
Laminin beta 1 chain precursor antibody
Laminin beta1 antibody
Laminin subunit beta 1 antibody
Laminin subunit beta-1 antibody
Laminin-1 subunit beta antibody
Laminin-10 subunit beta antibody
Laminin-12 subunit beta antibody
Laminin-2 subunit beta antibody
Laminin-6 subunit beta antibody
Laminin-8 subunit beta antibody
LIS5 antibody
MGC142015 antibody

Accession NoSwiss-Prot#:P07942

Uniprot P07942

Gene ID 3912;

Calculated MW198 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000
IHC: 1:100-1:500


FC: 1:50-1:100
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Laminin beta 1 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-Laminin beta 1 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse prostate tissue using anti-Laminin beta 1 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Laminin beta 1 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse small intestine tissue using anti-Laminin beta 1 antibody. Counter stained with hematoxylin.
Flow cytometric analysis of A431 cells with Laminin beta 1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the s?��?��??��?�c��%?
Laminins are essential and abundant structural non-collagenous glyco- proteins localizing to basement membranes. Basement membranes (cell-associated extracellular matrices (ECMs)) are polymers of laminins with stabilizing type IV collagen networks, nidogen, and several proteoglycans. Basement membranes are found under epithelial layers, around the endothelium of blood vessels, and surrounding muscle, peripheral nerve, and fat cells. Formation of basement membranes influences cell proliferation, phenotype, migration, gene expression, and tissue architecture. Each laminin is a heterotrimer of a, b, and g chain subunits that undergoes cell-secretion and incorporation into the ECM. Laminins can self-assemble, bind to other matrix macromolecules, and have unique and shared cell interactions mediated by integrins, dystroglycan, and cognate laminin receptors. The human Laminin b-1 gene maps to chromosome 7q22 and is ubiquitously expressed in tissues that produce basement membranes.

If you have published an article using product 49427, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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