Product Detail
Product NameCD32 Rabbit mAb
Clone No.JM10-70
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IHC
Species ReactivityHu
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other NamesCD32 antibody
CD32A antibody
CD32B antibody
CD32C antibody
CDw32 antibody
Fc fragment of IgG low affinity IIa receptor antibody
Fc fragment of IgG low affinity IIa receptor for (CD32) antibody
Fc fragment of IgG low affinity IIb receptor antibody
Fc fragment of IgG low affinity IIb receptor for (CD32) antibody
Fc fragment of IgG low affinity IIc receptor antibody
Fc fragment of IgG low affinity IIc receptor for (CD32) antibody
Fc fragment of IgG, low affinity II, receptor for (CD32) antibody
Fc fragment of IgG, low affinity IIa, receptor (CD32) antibody
Fc fragment of IgG, low affinity IIb, receptor (CD32) antibody
Fc gamma receptor IIB antibody
Fc gamma receptor IIC antibody
Fc gamma RII a antibody
Fc gamma RII b antibody
Fc gamma RII c antibody
Fc gamma RIIb antibody
Fc gamma RIIc antibody
Fc receptor, IgG, low affinity IIb antibody
Fc-gamma RII-a antibody
Fc-gamma RII-b antibody
Fc-gamma RII-c antibody
Fc-gamma-RIIa antibody
FC-gamma-RIIB antibody
Fc-GAMMA-RIIC antibody
Fc[g]RII antibody
FCG2 antibody
FCG2A_HUMAN antibody
FcGR antibody
FCGR2 antibody
FCGR2A antibody
FCGR2A1 antibody
FCGR2B antibody
FCGR2C antibody
Fcgr3 antibody
Fcgr3a antibody
FcgRII antibody
Fcr-2 antibody
Fcr-3 antibody
FcRII a antibody
FCRII antibody
FcRII b antibody
FcRII c antibody
FcRII-a antibody
FcRIIC antibody
IGFR2 antibody
IgG Fc receptor II a antibody
IgG Fc receptor II b antibody
IgG Fc receptor II beta antibody
IgG Fc receptor II c antibody
IgG Fc receptor II-a antibody
IgG Fc receptor II-b antibody
IgG Fc receptor II-c antibody
Immunoglobulin G Fc receptor II antibody
Immunoglobulin G Fc receptor II c antibody
Low affinity immunoglobulin gamma Fc region receptor II antibody
Low affinity immunoglobulin gamma Fc region receptor II-a antibody
Low affinity immunoglobulin gamma Fc region receptor II-b antibody
Low affinity immunoglobulin gamma Fc region receptor II-c antibody
Ly-17 antibody
Ly-m20 antibody
LyM-1 antibody
Lymphocyte antigen 17 antibody
Accession NoSwiss-Prot#:P12318
Uniprot
P12318
Gene ID
2212;
Calculated MW45 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:1,000-5,000
IHC: 1:50-1:200
Western blot analysis of CD32 on human lung cells lysates using anti-CD32 antibody at 1/500 dilution.
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD32 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD32 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-CD32 antibody. Counter stained with hematoxylin.
CD32 (also designated Fc gamma RII) is a low affinity receptor for the Fc fragment of aggregated IgG (1,2). CD32 is responsible for the clearance of immunocomplexes by macrophages and also plays an important role in the regulation of antibody production by B cells (1-4). IgG can noncooperatively bind either one or two highly glycosylated CD32 molecules, and this binding delivers a negative signal for B cells (1,2,5). CD32 exists as several isoforms that are produced by alternative splicing of three distinct genes, A, B, and C (2,6). These isoforms are designated FcgRIIA, FcgRIIB1, FcgRIIB3, and FcgRIIC (1,2,6). All isoforms are present on monocytes, placental trophoblasts and endothelial cells (1,6). In addition, the FcgRIIB forms are present on B lymphocytes, and the FcgRIIA and FcgRIIC forms are found on neutrophils (1,6).
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