Product Detail
Product NameCD62P Rabbit mAb
Clone No.JM10-95
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IHC
Species ReactivityHu
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other NamesAntigen CD62 antibody
CD62 antibody
CD62 antigen-like family member P antibody
CD62P antibody
GMP 140 antibody
GMP-140 antibody
GMP140 antibody
GMRP antibody
Granule membrane protein 140 antibody
Granulocyte membrane protein antibody
GRMP antibody
LECAM 3 antibody
LECAM3 antibody
Leukocyte endothelial cell adhesion molecule 3 antibody
Leukocyte-endothelial cell adhesion molecule 3 antibody
LYAM3_HUMAN antibody
P Selectin antibody
P-selectin antibody
PADGEM antibody
Platelet activation dependent granule-external membrane protein antibody
Platelet alpha granule membrane protein antibody
PSEL antibody
Selectin P (granule membrane protein 140kDa, antigen CD62) antibody
SELP antibody
Accession NoSwiss-Prot#:P16109
Uniprot
P16109
Gene ID
6403;
Calculated MW100 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:1,000-1:2,000
IHC: 1:50-1:200
Western blot analysis of CD62P on different cells lysates using anti-CD62P antibody at 1/500 dilution. Positive control:
Line1: HUVEC
Line2: Human placenta
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD62P antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD62P antibody. Counter stained with hematoxylin.
Selectins, also designated CD62 antigens, comprise a family of carbohydrate-binding proteins involved in mediating cellular interactions with leukocytes. L-Selectin (also designated LECAM-1 or CD62L) is expressed on the majority of B and naive T cells and on most monocytes, neutrophils and eosinophils. L-Selectin interacts with specific carbohydrates expressed by activated endothelial cells. P-Selectin (also designated GMP-140 or CD62P), expressed on activated platelets and endothelial cells, and E-Selectin (also designated ELMA-1 or CD62E), expressed on endothelial cells, exhibit overlapping ligand specificities. Both recognize sialyl-Le (x) as a ligand and bind to specific carbohydrates on neutrophils and monocytes.
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