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Location： Home > Recombinant Rabbit Monoclonal Antibodies > Integrin beta 4 Rabbit mAb

Integrin beta 4 Rabbit mAb#49465

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Product Detail

Product NameIntegrin beta 4 Rabbit mAb

Clone No.JM11-06

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, IHC

Species ReactivityHu, Ms

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesCD 104 antibody
CD104 antibody
CD104 antigen antibody
gp150 antibody
Integrin beta 4 subunit antibody
Integrin beta-4 antibody
ITB4_HUMAN antibody
ITG B4 antibody
ITGB 4 antibody
Itgb4 antibody

Accession NoSwiss-Prot#:P16144

Uniprot P16144

Gene ID 3691;

Calculated MW210 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000-1:2,000
IHC: 1:50-1:200


Western blot analysis of Integrin beta 4 on Jurkat cells lysates using anti-Integrin beta 4 antibody at 1/500 dilution. Positive control��
Line 1: A431
Line 2: A549
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti-Integrin beta 4 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Integrin beta 4 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-Integrin beta 4 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-Integrin beta 4 antibody. Counter stained with hematoxylin.
Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen and vitronectin. Certain integrins can also bind to soluble ligands, such as fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Integrin β4 (ITGB4), also known as CD104, is a 1,822 amino acid single-pass type I membrane protein belonging to the Integrin β chain family. Known to associate with Integrin α6, Integrin β4 functions as a receptor for Laminin and is predominantly expressed by epithelia. Integrin β4 exists as five alternatively spliced isoforms that are encoded by a gene located on human chromosome 17q25.1.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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