Welcome to Sabbiotech!     
Email:info@signalwayantibody.com
Welcome Login Register My Cart(0,$0.00)
Location： Home > Recombinant Rabbit Monoclonal Antibodies > RPE65 Rabbit mAb

RPE65 Rabbit mAb#49495

Datasheet PDF
Availability： Yes
Total Amount:$
ADD TO CART
Detail Pictures Description Publish(1) Other
Product Detail

Product NameRPE65 Rabbit mAb

Clone No.JM61-51

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, IP

Species ReactivityHu, Ms, Rt

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesAll-trans-retinyl-palmitate hydrolase antibody
LCA 2 antibody
LCA2 antibody
Leber congenital amaurosis antibody
mRPE 65 antibody
mRPE65 antibody
p63 antibody
rd 12 antibody
rd12 antibody
Retinal pigment epithelium specific 61 kDa protein antibody
Retinal pigment epithelium specific 65 kDa protein antibody
Retinal pigment epithelium specific protein antibody
Retinal pigment epithelium specific protein 65kDa antibody
Retinal pigment epithelium-specific 65 kDa protein antibody
Retinitis pigmentosa 20 antibody
Retinoid isomerohydrolase antibody
Retinol isomerase antibody
RP 20 antibody
RP20 antibody
RPE 65 antibody
RPE65 antibody
RPE65_HUMAN antibody
sRPE 65 antibody
sRPE65 antibody

Accession NoSwiss-Prot#:Q16518

Uniprot Q16518

Gene ID 6121;

Calculated MW61 kDa

Concentration1 mg/mL

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details

WB: 1:1,000-1:2,000


IP: 1:10-1:50

Western blot analysis of RPE65 on mouse eyeball cells lysates using anti-RPE65 antibody at 1/500 dilution.

The retinal pigment epithelium (RPE) is a monolayer simple epithelium in proximity to the outer surface of the retinal photoreceptor cells. Retinal pigment epithelium-specific protein (RPE65) is a 65kDa protein belonging to the beta-carotene dioxygenase family. This protein is important in 11-cis retinal production as well as in visual pigment regeneration. RPE65 is attached to the membrane by a lipid anchor when palmitoylated (membrane form) and soluble when unpalmitoylated. The soluble form of the protein binds vitamin A. Defects in RPE65 causes autosomal dominant retinitis pigmentosa and/or Leber congenital amaurosis type 2.

If you have published an article using product 49495, please notify us so that we can cite your literature.

et al,Suppressing endoplasmic reticulum stress-related autophagy attenuates retinal light injury. In Aging (Albany NY) on 2020 Aug 28 by Jing-Yao Song, Bin Fan,et al..PMID: 32858529 , (2020),
PMID: 32858529

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
;

QUICK NAV

New Products

Cell Signal Transduction

Cancer

Stem Cell

Neuroscience

Help and Support

Contact Us

Terms

Privacy Policy

support

Distributors