Product Detail
Product NameBid Rabbit mAb
Clone No.JM11-14
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, ICC/IF, IHC, FC, IP
Species ReactivityHu
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other NamesApoptic death agonist antibody
Apoptotic death agonist BID antibody
BH3 interacting domain death agonist antibody
BH3 interacting domain death agonist p11 antibody
BH3 interacting domain death agonist p13 antibody
BH3 interacting domain death agonist p15 antibody
BH3-interacting domain death agonist p11 antibody
BID antibody
BID isoform ES(1b) antibody
BID isoform L(2) antibody
BID isoform Si6 antibody
BID_HUMAN antibody
Desmocollin type 4 antibody
FP497 antibody
Human BID coding sequence antibody
MGC15319 antibody
MGC42355 antibody
p11 BID antibody
p13 BID antibody
p15 BID antibody
p22 BID antibody
Accession NoSwiss-Prot#:P55957
Uniprot
P55957
Gene ID
637;
Calculated MW22 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:1,000
IHC: 1:50-1:200
ICC: 1:50-1:200
IP: 1:10-1:50
FC: 1:50-1:100
Members of the Bcl-2 family of proteins interact to regulate programmed cell death, or apoptosis. Various homodimers and heterodimers formed by proteins in this family can either promote or inhibit apoptosis. Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect on certain hematopoietic cell lines following growth factor withdrawal. Additional apoptotic inhibitors in this family include A1, Bag-1, Bcl-w, Bcl-x and Mcl-1. Pro-apoptotic members of this family include Bax, Bad, Bak, Bik (NBK) and BID. BID contains a BH3 domain which allows it to dimerize with and counter the death repressor effects of Bcl-2. BID has also been shown to heterodimerize with Bcl-x and the death agonist Bax. BID is localized predominantly in the cytosol and is also present in membrane fractions. It is highly expressed in kidney and can also be detected in brain, spleen, liver, testis and lung.
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