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Location： Home > Recombinant Rabbit Monoclonal Antibodies > CD26 Rabbit mAb

CD26 Rabbit mAb#49506

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Product Detail

Product NameCD26 Rabbit mAb

Clone No.JM11-42

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, ICC/IF, IHC, FC

Species ReactivityHu, Ms, Rt

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesCD26 antigen antibody
ADA-binding protein antibody
ADABP antibody
ADCP 2 antibody
ADCP-2 antibody
ADCP2 antibody
Adenosine deaminase complexing protein 2 antibody
CD 26 antibody
CD26 antibody
CD26 antigen 3 antibody
Dipeptidyl peptidase 4 antibody
Dipeptidyl peptidase 4 soluble form antibody
Dipeptidyl peptidase IV antibody
Dipeptidyl peptidase IV membrane form antibody
Dipeptidyl peptidase IV soluble form antibody
Dipeptidyl peptidase, intestinal antibody
Dipeptidylpeptidase 4 antibody
Dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2) antibody
Dipeptidylpeptidase IV antibody
DPP 4 antibody
DPP IV antibody
DPP IV estoenzyme antibody
DPP4 antibody
DPP4_HUMAN antibody
DPPIV antibody
Intestinal dipeptidyl peptidase antibody
T cell activation antigen CD26 antibody
T-cell activation antigen CD26 antibody
TP 103 antibody
TP103 antibody

Accession NoSwiss-Prot#:P27487

Uniprot P27487

Gene ID 1803;

Calculated MW110 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:500-1:2,000
IHC: 1:50-1:100
ICC: 1:50-1:200

FC: 1:50-1:100
CD26 (dipeptidylpeptidase 4, adenosine deaminase complexing protein 2, ADABP, ADCP2, DPPIV, TP103) is a membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. CD26 has an essential role in immune regulation as a T cell activation molecule and a regulator of chemokine function. CD26 associates with CXCR4 and gp120 and may influence the pathophysiology of HIV infection. Adenosine deaminase (ADA) colocalizing with adenosine receptors on dendritic cells are able to interact with CD26 expressed on lymphocytes. This costimulatory signal in the immunological synapse leads to an increase in the production of the T helper 1 and proinflammatory cytokines IFN-gamma, TNF-alpha, and IL-6. CD26 plays a role in the pathogenesis and behavior of human cancers, including solid tumors and hematological malignancies. CD26-caveolin-1 interaction plays a role in the up-regulation of CD86 on TT-loaded monocytes and subsequent engagement with CD28 on T cells, leading to antigen-specific T cell activation.

If you have published an article using product 49506, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
;

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