Product Detail
Product NameRhodopsin Rabbit mAb
Clone No.JA10-91
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IHC
Species ReactivityHu, Rt
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other NamesCSNBAD1 antibody
MGC138309 antibody
MGC138311 antibody
OPN 2 antibody
OPN2 antibody
opsd antibody
OPSD_HUMAN antibody
opsin 2 antibody
Opsin 2 rod pigment antibody
Opsin-2 antibody
Opsin2 antibody
Retinitis Pigmentosa 4 antibody
Retinitis pigmentosa 4 autosomal dominant antibody
RHO antibody
Rhodopsin antibody
RP 4 antibody
RP4 antibody
Accession NoSwiss-Prot#:P08100
Uniprot
P08100
Gene ID
6010;
Calculated MW39 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:1,000
IHC: 1:50-1:200
Immunohistochemical analysis of paraffin-embedded rat retina tissue using anti-Rhodopsin antibody. Counter stained with hematoxylin.
In aerobic respiration reactions, succinate dehydrogenase (SDH) catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol. Four subunits comprise the SDH protein complex: a flavochrome subunit (SDHA), an iron-sulfur protein (SDHB), and two membrane-bound subunits (SDHC and SDHD) anchored to the inner mitochondrial membrane. Mutations to these subunits cause mitochondrial dysfunction, corresponding to several distinct disorders. Mutations in the membrane bound components may cause hereditary paraganglioma, while SDHA mutations are associated with juvenile encephalopathy as well as Leigh Syndrome, a severe neurological disorder. Inactivating mutations in SDHB correlate with inherited, but not necessarily sporadic, cases of pheochromocytoma.
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