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Location： Home > Recombinant Rabbit Monoclonal Antibodies > alpha sarcoglycan Rabbit mAb

alpha sarcoglycan Rabbit mAb#49537

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Product Detail

Product Namealpha sarcoglycan Rabbit mAb

Clone No.JA51-81

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, IP, IHC

Species ReactivityHu, Ms, Rt

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other Names50 DAG antibody
50 kDa dystrophin associated glycoprotein antibody
50 kDa dystrophin-associated glycoprotein antibody
50DAG antibody
50kD DAG antibody
59kDa antibody
A2 antibody
adhalin antibody
ADL antibody
Alpha SG antibody
Alpha-sarcoglycan antibody
Alpha-SG antibody
Asg antibody
DAG2 antibody
DMDA2 antibody
Dystroglycan 2 antibody
Dystroglycan-2 antibody
LGMD2D antibody
sarcoglycan, alpha (dystrophin-associated glycoprotein) antibody
SCARMD1 antibody
Sgca antibody
SGCA_HUMAN antibody

Accession NoSwiss-Prot#:Q16586

Uniprot Q16586

Gene ID 6442;

Calculated MW50 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:500-1:2,000
IHC: 1:50-1:200

IP: 1:50-1:100
Western blot analysis of alpha sarcoglycan on rat heart cells lysates using anti-alpha sarcoglycan antibody at 1/500 dilution.
Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-alpha sarcoglycan antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue using anti-alpha sarcoglycan antibody. Counter stained with hematoxylin.
The sarcoglycan transmembrane proteins are members of the dystrophin complex. Sarcoglycans cluster together to form a complex, which is localized in the cell membrane of skeletal, cardiac, and smooth muscle fibers. Four sarcoglycan subunit proteins, designated α-, β-, γ- and δ-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, β- and δ-sarcoglycans are associated with ε-sarcoglycan, a glycoprotein homologous to α-sarcoglycan. Additionally, a complete deficiency in δ-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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