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Location： Home > Recombinant Rabbit Monoclonal Antibodies > CD163 Rabbit mAb

CD163 Rabbit mAb#49553

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Product Detail

Product NameCD163 Rabbit mAb

Clone No.JA51-30

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, IHC, IP, FC

Species ReactivityHu

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesC163A_HUMAN antibody
CD 163 antibody
CD163 antibody
CD163 antigen antibody
CD163 molecule antibody
Hemoglobin scavenger receptor antibody
M130 antibody
M130 antigen precursor antibody
Macrophage associated antigen antibody
MM130 antibody
OTTHUMP00000238617 antibody
OTTHUMP00000238618 antibody
OTTHUMP00000238619 antibody
OTTHUMP00000238620 antibody
SCARI1 antibody
Scavenger receptor cysteine rich type 1 protein M130 antibody
sCD163 antibody
Soluble CD163 antibody

Accession NoSwiss-Prot#:Q86VB7

Uniprot Q86VB7

Gene ID 9332;

Calculated MW150 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:500-1:2,000
IHC: 1:50-1:200


FC: 1:50-1:100
Western blot analysis of CD163 on human thymus tissue lysate using anti-CD163 antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-CD163 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD163 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-CD163 antibody. Counter stained with hematoxylin.
Flow cytometric analysis of THP-1 cells with CD163 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
CD163, also designated M130, is a macrophage-associated antigen that is a member of the scavenger receptor cysteine-rich (SRCR) superfamily. It is highly expressed on macrogphages and to a lesser extent on monocytes. The acute phase-regulated and signal-inducing macrophage protein, CD163, is a receptor that scavenges hemoglobin by mediating endocytosis of haptoglobin-hemoglobin complexes. CD163 binds only haptoglobin and hemoglobin in complex, which indicates the exposure of a receptor-binding neoepitope. The receptor-ligand interaction is calcium-dependent and of high affinity. The existence of several CD163 isoforms, which differ in the structure of their cytoplasmic domains and putative phosphorylation sites, suggests that these isoforms also differ in their signaling mechanism. The gene which encodes CD163 maps to human chromosome 12p13.31.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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