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Location： Home > Recombinant Rabbit Monoclonal Antibodies > CD39 Rabbit mAb

CD39 Rabbit mAb#49579

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Product Detail

Product NameCD39 Rabbit mAb

Clone No.JA90-36

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, IHC

Species ReactivityHu, Ms, Rt

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesATPDase antibody
CD 39 antibody
CD39 antibody
CD39 antigen antibody
DKFZp686D194 antibody
DKFZp686I093 antibody
Ecto apyrase antibody
Ecto ATP diphosphohydrolase antibody
Ecto-apyrase antibody
Ecto-ATP diphosphohydrolase 1 antibody
Ecto-ATPase 1 antibody
Ecto-ATPDase 1 antibody
Ectonucleoside triphosphate diphosphohydrolase 1 antibody
ENTP1_HUMAN antibody
ENTPD 1 antibody
ENTPD1 antibody
FLJ40921 antibody
FLJ40959 antibody
Lymphoid cell activation antigen antibody
NTPDase 1 antibody
NTPDase1 antibody
SPG64 antibody

Accession NoSwiss-Prot#:P49961

Uniprot P49961

Gene ID 953;

Calculated MW70 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:500-1:1,000
IHC: 1:50-1:200


Western blot analysis of CD39 on different cell lysate using anti-CD39 antibody at 1/1,000 dilution.
Positive control��
Lane1: Human spleen
Lane2: Mouse placenta
Lane3: Mouse spleen
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD39 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD39 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-CD39 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse uterus tissue using anti-CD39 antibody. Counter stained with hematoxylin.
CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENP1), is an integral membrane glycoprotein that acts as an extracellular nucleotide-hydrolyzing enzyme. CD39 inhibits ADP-induced platelet aggregation by hydrolyzing ADP to AMP and ultimately generating adenosine. Intracellular CD39 undergoes glycosylation at 6 N-glycosylation sites and translocates to the membrane in order to be an active enzyme. Alternative splicing gives rise to three CD39 isoforms, vascular, placenta I and placenta II. The placenta I isoform differs at the amino terminus whereas the placenta II isoform is missing amino acids 300-510 at the C-terminus. CD39 is expressed in vascular tissues including placenta, lung, skeletal muscle and kidney, as well as endothelium, smooth muscle, cardiac cells, lymphocytes (such as activated B cells) activated NK cells, macrophages, dendridic cells and platelets. CD39 may be used as an anti-thrombic agent for pre-treating patients at risk for coronary artery occlusion and thrombic stroke.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
;

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