Product Detail
Product NameIP3 Receptor Rabbit mAb
Clone No.JA11-35
Host SpeciesRecombinant Rabbit
ClonalityMonoclonal
PurificationProA affinity purified
ApplicationsWB, IHC
Species ReactivityHu, Ms, Rt
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other Names4 antibody
5-trisphosphate receptor antibody
5-trisphosphate receptor type 1 antibody
DKFZp313E1334 antibody
DKFZp313N1434 antibody
inositol 1 4 5 triphosphate receptor type 1 antibody
Inositol 1 4 5 trisphosphate Receptor Type 1 antibody
Inositol 1 antibody
InsP3R1 antibody
IP3 antibody
IP3 receptor antibody
IP3 receptor isoform 1 antibody
IP3R 1 antibody
IP3R antibody
IP3R1 antibody
ITPR 1 antibody
Itpr1 antibody
ITPR1_HUMAN antibody
SCA15 antibody
SCA16 antibody
SCA29 antibody
Type 1 inositol 1 4 5 trisphosphate receptor antibody
Type 1 inositol 1 antibody
Type 1 InsP3 receptor antibody
Accession NoSwiss-Prot#:Q14643
Uniprot
Q14643
Gene ID
3708;
Calculated MW314 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500
IHC: 1:50-1:200
Immunohistochemical analysis of paraffin-embedded mouse hippocampus tissue using anti-IP3 Receptor antibody. Counter stained with hematoxylin.
Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.
If you have published an article using product 49582, please notify us so that we can cite your literature.
Yes
