Product Detail
Product NameOGG1 Rabbit mAb
Clone No.JA18-13
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IHC
Species ReactivityHu
Immunogen DescRecombinant protein
ConjugateUnconjugated
Other Names8 hydroxyguanine DNA glycosylase antibody
8 oxoguanine DNA glycosylase 1 antibody
8 oxoguanine DNA glycosylase antibody
AP lyase antibody
DNA (apurinic or apyrimidinic site) lyase antibody
DNA apurinic or apyrimidinic site lyase antibody
DNA lyase antibody
DNA-(apurinic or apyrimidinic site) lyase antibody
HMMH antibody
HOGG 1 antibody
HOGG1 antibody
MMH antibody
MUTM antibody
N glycosylase antibody
Ogg 1 antibody
Ogg1 antibody
OGG1_HUMAN antibody
OGH 1 antibody
OGH1 antibody
Accession NoSwiss-Prot#:O15527
Uniprot
O15527
Gene ID
4968;
Calculated MW39 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500
IHC: 1:50-1:200
DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion. The OGG1 gene encodes 8 isoforms (OGG1A-C, OGG2A-E) which result from alternative splicing of a single messenger RNA. The OGG1A splice variant is the most prevalent form and localizes to the nucleus, whereas the OGG2A splice variant is targeted to the mitochondria.
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