Product Detail
Product NameCytochrome P450 3A4 Rabbit mAb
Clone No.JA11-33
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IHC, IP
Species ReactivityHu
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other Names1,8-cineole 2-exo-monooxygenase antibody
Albendazole monooxygenase antibody
Albendazole sulfoxidase antibody
CP33 antibody
CP34 antibody
CP3A4_HUMAN antibody
CYP3 antibody
CYP3A antibody
CYP3A3 antibody
CYP3A4 antibody
CYPIIIA3 antibody
CYPIIIA4 antibody
Cytochrome P450 3A3 antibody
Cytochrome P450 3A4 antibody
Cytochrome P450 family 3 subfamily A polypeptide 4 antibody
Cytochrome P450 HLp antibody
Cytochrome P450 NF-25 antibody
Cytochrome P450 subfamily IIIA polypeptide 4 antibody
cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3 antibody
cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 antibody
Cytochrome P450-PCN1 antibody
Glucocorticoid inducible P450 antibody
HLP antibody
MGC126680 antibody
NF 25 antibody
NF25 antibody
Nifedipine oxidase antibody
P450 III steroid inducible antibody
P450 PCN1 antibody
P450, family III antibody
P450C3 antibody
P450PCN1 antibody
Quinine 3 monooxygenase antibody
Quinine 3-monooxygenase antibody
Taurochenodeoxycholate 6 alpha hydroxylase antibody
Taurochenodeoxycholate 6-alpha-hydroxylase antibody
Accession NoSwiss-Prot#:P08684
Uniprot
P08684
Gene ID
1576;
Calculated MW57 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:1,000
IHC: 1:50-1:200
Western blot analysis of Cytochrome P450 3A4 on human liver tissue lysate using anti-Cytochrome P450 3A4 antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Cytochrome P450 3A4 antibody. Counter stained with hematoxylin.
CYP3A, the most abundant p450 enzyme in human liver, is responsible for the metabolism of more than 50% of the clinical test & lt; RTI ID = 0.0 & gt; (cYP3A) genes encode monooxygenases-enzymes which catalyze drug metabolism and the synthesis of cholesterol, steroids and other lipids. CYP3A family members localize in organs that associate with drug disposition, including the liver, gastrointestinal tract and kidney. The CYP3A cluster maps to gene locus 7q22.1 and consists of four genes (CYP3A4, CYP3A5, CYP3A7 and CYP3A43) and two pseudogenes ( CYP3A4 is abundant in the endoplasmic reticulum of liver cells and upper intestinal enterocytes. CYP3A4 expression is isducible by glucocorticoids pharmacological agents.
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