Product Detail
Product NameCalretinin Rabbit mAb
Clone No.JM12-93
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IHC
Species ReactivityHu, Ms, Rt
Immunogen DescRecombinant protein
ConjugateUnconjugated
Other Names29 kDa calbindin antibody
CAB 29 antibody
CAB29 antibody
CAL 2 antibody
CAL2 antibody
CALB 2 antibody
CALB2 antibody
CALB2_HUMAN antibody
Calbindin 2 29kDa antibody
Calbindin 2 antibody
Calbindin D29K antibody
Calbindin2 antibody
Calretinin antibody
CR antibody
Accession NoSwiss-Prot#:P22676
Uniprot
P22676
Gene ID
794;
Calculated MW31 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500
IHC: 1:50-1:200
Calbindin D28K and Calretinin (also designated CR or 29 kDa Calbindin) are two closely related intracellular calcium-binding proteins belonging to the Troponin-C superfamily. Initially isolated from chick retina, Calretinin shares 58% identical residues with human Calbindin D28K. Calretinin is expressed in the brain and is particularly abundant in auditory neurons with precisely timed discharges. Neurons in the nucleus accumbens containing Calretinin all possess nuclear indentations. Calretinin-immunoreactive boutons form asymmetrical and symmetrical synaptic specializations on spines, dendrites and somata. The symmetrical synaptic specializations have medium-sized spiny neurons and contact other Calretinin-immunoreactive somata. Calretinin is widely used as a immunocytochemical marker for mesothelioma.
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